The Uses of and Poisoning by the Barbiturates
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منابع مشابه
Silent Cocaine Poisoning
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Hospital admissions due to acute barbiturate poisoning per million population in England and Wales have decreased since 1965 at about the same rate as NHS prescriptions for barbiturates. Admissions due to poisoning with other drugs have increased, but, largely because the benzodiazepine hypnotics and tranquillisers are much less toxic than the barbiturates that they are replacing, deaths from p...
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The new 4'- hydroxy and 3'- aldehyde phase- 1 metabolites of butobarbitone and pentobarbitone are fully synthesized for the first time. These metabolites were used to idenfity and quantify the natural metabolites in human urine after single and multiple doses of these drugs. The synthesized metobolites have spectral characterizations (IR, NMR, U.V. and mass spectroscopy) consisted with the ...
متن کاملPatterns of self poisoning.
A population of 935 hospital admissions for self poisoning over a five-year period, 1967-71, was taken from three general hospitals in the Chichester area. All admissions were followed up by use of coroner's records. The peak age group for accidental self poisonings was 0-9 with a further peak in the over 60 age group. The peak age for attempted suicides was 20-29. There were more women than me...
متن کاملQSAR models to predict physico-chemical Properties of some barbiturate derivatives using molecular descriptors and genetic algorithm- multiple linear regressions
In this study the relationship between choosing appropriate descriptors by genetic algorithm to the Polarizability (POL), Molar Refractivity (MR) and Octanol/water Partition Coefficient (LogP) of barbiturates is studied. The chemical structures of the molecules were optimized using ab initio 6-31G basis set method and Polak-Ribiere algorithm with conjugated gradient within HyperChem 8.0 environ...
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تاریخ انتشار 2016